Publications
Underlined = first/corresponding author (or joint)
Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTLab cassette-based platform; Z. Yang, C. Barnes, J. Domarkas, J. Koch-Paskowski, J. Wright, A. Amgheib, I. Renard, R. Fu, S. J. Archibald, E. O. Aboagye* and L. Allott*; RSC React. Chem. Eng., 2023
Design, synthesis and evaluation of a novel PET imaging agent targeting lipofuscin in senescent cells; D. Brickute, C. Chen, M. Braga, C. Barnes, N. Wang, L. Allott* and E. O. Aboagye*. RSC Adv., 2022, 12, 26372-26381.
A practical guide to automating fluorine-18 PET radiochemistry using commercially available cassette-based platforms; C. Barnes, M. Nair, E. O. Aboagye, S. J. Archibald and L. Allott*. React. Chem. Eng., 2022, 7, 2265-2279.
A kit-based aluminium-[18F]fluoride approach to radiolabelled microbubbles; J. H. Teh, M. Braga, L. Allott, C. Barnes, J. Hernandez-Gil, M. Tang, E. Aboagye and N. J. Long. Chem Commun, 2021, 57, 11677-11680
The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules; S. J. Archibald and L. Allott* EJNMMI Radiopharm. Chem., 2021, 6, 30
Consideration of Metabolic Efflux in Radiolabelled Choline Kinetics” Y. Li, M. Inglese, S. Dubash, C. Barnes, D. Brickute, M. Braga, N. Wang, A. Beckley, K. Heinzmann, L. Allott, H. Lu, C. Chen, R. Fu, L. Carroll and E. O. Aboagye. Pharmaceutics, 2021, 13(8):1246
Effective Detection and Monitoring of Glioma using [18F]FPIA PET Imaging; V. Vassileva, M. Braga, C. Barnes, J. Przystal, A. Ashek, L. Allott, D. Brickute, J. M. Abrahams, K. Suwan, A. M. Carcaboso, A. Hajitou and E. O. Aboagye. Biomedicines, 2021, 9(7):811.
Novel non-congeneric derivatives of the choline kinase alpha inhibitor ICL-CCIC-0019 ;N. Wang, D. Brickute, M. Braga, C. Barnes, H. Lu, L. Allott* and Eric O. Aboagye*. Pharmaceutics, 2021, 13, 1078
Detecting hypoxia in vitro using 18F-pretargeted IEDDA “click” chemistry in live cells; L. Allott, C. Chen, M. Braga, S. F. J. Leung, N. Wang, C. Barnes, D. Brickute, L. Carroll and E. O. Aboagye. RSC Adv., 2021, 33, 20335-20341
Radiolabelling an 18F biologic via facile IEDDA “click” chemistry on the GE FASTLab™ platform; L. Allott, A. Amgheib, C. Barnes, M. Braga, D. Brickute, N. Wang, R. Fu, S. Ghaem-Maghami and E. O. Aboagye. React. Chem. Eng., 2021, 6, 1070-1078
Synthesis and evaluation of 3’-[18F]fluorothymidine-5’-squaryl as a bioisostere of 3’-[18F]fluorothymidine-5’-monophosphate; D. Brickute, A. Beckley, L. Allott, M. Braga, C. Barnes, K. J. Thorley and E. O. Aboagye. RSC Adv., 2021, 20, 12423-12433
Chemistry considerations for the clinical translation of PET radiopharmaceuticals; L. Allott and E. O. Aboagye. Mol. Pharm., 2020; doi: 10.1021/acs.molpharmaceut.0c00328
Development of a fluorine-18 radiolabelled fluorescent chalcone: evaluated for detecting glycogen; L. Allott, D. Brickute, C. Chen, M. Braga, C. Barnes, N. Wang and E. O. Aboagye. EJNMMI Radiopharm. Chem., 2020; doi: 10.1186/s41181-020-00098-6
[18F]FET-βAG-TOCA: the design, evaluation and clinical translation of a fluorinated octreotide; L. Allott, S. Dubash and E. O. Aboagye. Cancers, 2020, 12, 856.
Clinical Translation of 18F-Fluoropivalate - A PET Tracer for Imaging Short-Chain Fatty Acid Metabolism: Safety, Biodistribution, and Dosimetry in Fed and Fasted Healthy Volunteers; S. R. Dubash, N. Keat, K. Kozlowski, C. Barnes, L. Allott, D. Brickute, S. Hill, M. Huiban, T. Barwick, L. Kenny, E. O. Aboagye. EJNMMI, 2020; doi: 10.1007/s00259-020-04724-y
Solid-supported cyanoborohydride cartridges for automating reductive amination radiochemistry; L. Allott, C. Barnes, J. S. F. Leung, D. Brickute and E. O. Aboagye, React. Chem. Eng., 2019, 4, 1748-1751.
Synthesis of a benzoxazinthione derivative of Tanaproget and pharmacological evaluation for PET imaging of PR expression; L. Allott, C. Miranda, A. Hayes, C. Cawthorne and G. Smith, EJNMMI Radiopharm. Chem., 2019, 4, 1-20.
An Improved Automated Radiosynthesis of [18F]FET-βAG-TOCA”; L. Allott, C. Barnes, D. Brickute and E. O. Aboagye; React. Chem. Eng., 2019, 4, 569-574.
Affibody-based PET imaging to guide EGFR-targeted cancer therapy in head and neck squamous cell cancer models; T. A. Burley, C. Da Pieve, C. D. Martins, D. M. Ciobota, L. Allott, W. J. G. Oyen, K. J. Harrington, G. Smith and G. Kramer-Marek; J. Nucl. Med., 2018, 60, 353-361.
HER3-Mediated Resistance to Hsp90 Inhibition Detected in Breast Cancer Xenografts by Affibody-based PET Imaging”; C. D. Martins, C. Da Pieve, T. A. Burley, R. Smith, D. M. Ciobota, L. Allott, K. Harrington, W. J.G. Oyen, G. Smith and G. Kramer-Marek; Clin. Cancer Res., 2018, 24, 1853-1865.
Evaluation of DFO-HOPO as an octadentate chelator for zirconium-89”; L. Allott, C. Da Pieve, J. Meyers, T. Spinks, D.M. Ciobota, G. Kramer-Marek and G. Smith; Chem. Commun., 2017, 53, 8529-8532.
A general [18F]AlF radiochemistry procedure on two automated synthesis platforms; L. Allott, C. Da Pieve, D. R. Turton and G. Smith; React. Chem. Eng., 2017, 2, 68-74.
Efficient [18F]AlF radiolabelling of ZHER3:8698 affibody molecule for imaging of HER3 positive tumours; C. Da Pieve, L. Allott, C. D. Martins, A. Vardon, C. M. Daniela, G. Kramer-Marek and G. Smith; Bioconj. Chem., 2016, 27(8).
Synthesis and preclinical evaluation of an [18F]fluoromethyl-Tanaproget derivative for imaging of prosterone receptor expression; S. Merchant, L. Allott, L. Carroll, V. Tittrea, S. Kealey, T. Witney, P. W. Miller, G. Smith and E. O. Aboagye; RSC Adv., 2016, 6(62).
Development of PDT/PET Theranostics: Synthesis and Biological Evaluation of a 18F-radiolabeleld water soluble porphyrin; G. Entract, F. Bryden, J. Domarkas, H. Savoie, L. Allott, S. J. Archibald, C. Cawthorne, and R. W. Boyle; Molecular Pharmaceutics, 2015, 12(12).
PET Imaging of Steroid Hormone Receptor Expression; L. Allott, G. Smith, E. O. Aboagye and L. Carroll; Molecular Imaging, 2015, 14(9):11-22.
Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget; T. Haywood, S. Kealey, S. S. Cabezas, J. J. Hall, L. Allott, G. Smith, C. Plisson and P. W. Miller; Chem. Eur. J., 2015, 21(25).
